BOTOX® Cosmetic (onabotulinumtoxinA) is a purified protein derived from the bacterium Clostridium botulinum.1 Botulinum toxins have been studied for more than 100 years.
In the late 1890s, scientists first identified C. botulinum as a cause of food poisoning (botulism). Scientists continued to study its effects, exploring its therapeutic uses in the late 1960s.2 By 1989, BOTOX® (onabotulinumtoxinA) was approved for medical use.3 The same product with dosing specific to glabellar lines was approved as BOTOX® Cosmetic in 2002.
The BOTOX® Cosmetic formulation
In nature, the botulinum neurotoxin associates with complementary nontoxic accessory proteins to produce protein complexes.4,5
BOTOX® Cosmetic (onabotulinumtoxinA) is a prescription medicine that is injected into muscles and used to temporarily improve the look of both moderate to severe crow’s feet lines and frown lines between the eyebrows in adults.
Check out some before and after photos: